![]() ![]() In a cross section, a tendon will usually appear round or oval in shape. A tendon comprises fascicles of collagen fibers, which run parallel along their axis. Tendons are generally resistant to extension, but flexible, meaning that they can be easily distorted around bones and joints. Tendons and ligaments attach to bones, and the role of dense regular connective tissue is to transfer forces to bones. A small amount of ground substance is present around dense regular connective tissue fibers and cells. This arrangement allows the fibers to have a good resistance to forces pulling along a single axis, but also gives some ability to stretch. The collagen fibers are densely packed together and arranged in parallel to each other. It is found in areas of the body where large amounts of tensile strength are required, like in ligaments, tendons and aponeurosis. Dense regular connective tissueĭense regular connective tissue is mainly made up of type I collagen fibers. It can be found in a number of locations within the body, including the dermis of the skin, in glandular tissue, in the walls of organs, and in the whites of the eyes. Its 3-dimensional structure allows it to withstand force from different directions. The 3-dimensional nature of dense irregular connective tissue gives it a great deal of strength.ĭense irregular connective tissue (histological slide)ĭense irregular connective tissue is found in high concentrations in body parts where support is needed to prevent the effects of forces that pull in multiple directions. The collagen fibers in dense irregular connective tissue are orientated randomly in a compact interwoven 3-dimensional web. Collagen fibers have good tensile strength and are therefore important in support. It contains molecules such as proteoglycans and adhesive glycoproteins, and like collagen fibers are produced by fibroblasts. Ground substance is amorphous and gel-like in texture that surrounds cells. Among the collagen fibers there is a network of elastic fibers as well, to limit the distensibility of the tissue. The type I collagen fibers of the dense irregular connective tissue are surrounded by small amounts of ground substance. Fibrils assemble to form collagen fibers. Three stranded collagen molecules are packed together to form collagen fibrils and their alignment yield characteristic ultrastructural striations. It has many types but in dense connective tissue mainly type I collagen is present. Learn everything about the dense connective tissue with the following study unit:Ĭollagen fibers are tough, thick fibrous proteins found in dense connective tissues. Overall, these cells exhibit the properties of fibroblasts as well as smooth muscle cells. The myofibroblasts are characterized by the presence of actin filaments and dense bodies. Specialised form of fibroblasts known as myofibroblasts also appear during wound contraction. In general, fibroblasts become very active during wound repair and healing process, when they proliferate and form fibrous matrix. Fibrocytes are fewer in number in circulation but have been shown to increase in quantity due to any pathology such as tissue damage, causing them to become activated and to display the properties of both fibroblasts and macrophages.ĭo you prefer to learn with interactive study tools? Look no further than our connective tissue quizzes and diagram labeling activities. The old and inactive fibroblasts, also known as fibrocytes have reduced cytoplasm with few cell organelles and flattened heterochromatic nuclei. Dense regular collagenous connective tissue (histological slide) ![]()
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